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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG1
All Species:
15.76
Human Site:
S408
Identified Species:
49.52
UniProt:
Q13976
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13976
NP_001091982.1
671
76364
S408
R
Q
Q
E
H
I
R
S
E
K
Q
I
M
Q
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851997
510
57367
L285
E
V
C
L
G
G
E
L
W
T
I
L
R
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P0C605
671
76332
S408
R
Q
Q
E
H
I
R
S
E
K
Q
I
M
Q
G
Rat
Rattus norvegicus
Q64595
762
87163
S500
K
Q
Q
E
H
V
Y
S
E
K
R
I
L
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03043
1088
121322
S825
R
Q
Q
Q
H
I
M
S
E
K
E
I
M
G
E
Honey Bee
Apis mellifera
NP_001011581
678
77281
S415
R
Q
Q
Q
H
I
M
S
E
K
R
I
M
G
E
Nematode Worm
Caenorhab. elegans
O76360
780
86723
A517
R
Q
Q
E
H
I
F
A
E
R
N
I
M
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
L155
D
Y
I
E
G
G
E
L
F
S
L
L
R
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.6
N.A.
99.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.9
61.2
45.1
N.A.
Protein Similarity:
100
N.A.
N.A.
72.2
N.A.
99.8
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
75.9
61.6
N.A.
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
66.6
60
N.A.
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
100
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
80
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
13
0
0
63
0
0
25
0
75
0
13
0
0
13
50
% E
% Phe:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
25
25
0
0
0
0
0
0
0
25
25
% G
% His:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
63
0
0
0
0
13
75
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
63
0
0
0
13
0
% K
% Leu:
0
0
0
13
0
0
0
25
0
0
13
25
13
0
0
% L
% Met:
0
0
0
0
0
0
25
0
0
0
0
0
63
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
75
75
25
0
0
0
0
0
0
25
0
0
25
0
% Q
% Arg:
63
0
0
0
0
0
25
0
0
13
25
0
25
0
13
% R
% Ser:
0
0
0
0
0
0
0
63
0
13
0
0
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% T
% Val:
0
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _